A DISTAL INTERGENIC REGION CONTROLS PANCREATIC ENDOCRINE DIFFERENTIATION BY ACTING AS A TRANSCRIPTIONAL ENHANCER AND AS A POLYCOMB RESPONSE ELEMENT.

A distal intergenic region controls pancreatic endocrine differentiation by acting as a transcriptional enhancer and as a polycomb response element.

Lineage-selective expression of developmental genes is dependent on the interplay between activating and repressive mechanisms.Gene activation is dependent on cell-specific transcription factors that recognize transcriptional enhancer sequences.Gene repression often depends on the recruitment of Polycomb group (PcG) proteins, although the sequences

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Efficacy of Lockdowns in Africa

The novel coronavirus has troubled the world, unleashing deaths and a social quagmire.The catastrophic implications of the pandemic pushed states to the brink, compelling them to institute country lockdowns in a bid to flatten the curve of infections, avoid new ones 1969 corvette seat covers and ensure that the health systems are not overwhelmed at

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